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The studies with a quality score of 7 or more had a higher OR compared to those with a score of less than 7

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GABA was reduced in patients versus controls across dACC and occipital voxels

After treatment, brain tissues were harvested and evaluated for oxidative stress biomarkers (8-OHdG, MDA, GPx, GSH, GST, SOD), pro-inflammatory cytokines (MPO, NF-B, TNF-), ion transport enzymes (Na/K ATPase, Ca ATPase), neurotransmitter levels (dopamine, serotonin, AChE), and the apoptotic marker caspase-3

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