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Description
These differences are particularly relevant for nanoparticle-associated cargos and receptor-targeted delivery systems, as transporter kinetics and receptor availability observed in mouse models may not accurately predict human brain penetration, retention, or therapeutic response
10.1038/s41392-023-01588-0 91 GasanoffE.LiuY.LiF.HanlonP.GarabG
It is not intended for human consumption or for use in therapeutic, diagnostic, or clinical settings
The treatment group showed lower mortality than controls, and no significant adverse effects were reported
PMID: 6907091
