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In hepatocytes, the key factors that regulate cysteine availability include membrane transport of cysteine (via the ASC system), cystine (via the X c - system which is induced under oxidative stress), methionine (via the L system) and the activity of the transsulfuration pathway [47,52,53]

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A study in the Journal of Controlled Release confirmed that microneedling enhances peptide penetration through the stratum corneum by up to 10-fold (PMC3016279)

Contribution of the diverse experimental models to unravelling the biological scope of dietary (poly)phenols