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Description
Opioid use disorder induces oxidative stress and inflammation

ROS can oxidize organelles, nucleic acids, proteins and lipids, which results in cellular damage [51]

Idiopathic inflammatory diseases Necrotizing meningoencephalitis and necrotizing leukoencephalitis of Pugs and other small-breed dogs Canine necrotizing meningoencephalitis (NME), formerly Pug dog encephalitis, is an idiopathic disease affecting mainly Pug dogs, but also reported rarely in the Maltese, Pekingese, Shih Tzu, and Chihuahua

doi: 10.1159/000430271

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
