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Overall, renal Oat1 expression is androgen-regulated, renal Oat2 expression is modulated by female GH secretion pattern, and hepatic Oat3 expression is influenced by both androgens and female GH secretion pattern (Buist et al., 2003)

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Due to its ability to cross the bloodbrain barrier, Orexin-A remains a molecule of interest in central nervous system signaling research

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