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Additionally, autophagy, which is responsible for the elimination of damaged mitochondria, may become dysregulated, resulting in the accumulation of dysfunctional mitochondria and thus cellular malfunction (42)

Damaged hepatocytes may release massive amounts of cell contents, such as nuclear DNA fragments, mitochondrial DNA, high mobility group box-1 (HMGB1), and ATP

Muscle development is influenced by a combination of growth signalling, hormone regulation, energy availability, and tissue adaptation

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