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Clinical protocols from Oregon Health & Science University indicate that occasional missed doses dont cause severe consequences, but maintaining consistent timing optimizes severe asthma management outcomes

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The compound moved through Phase I trials, which primarily assess safety in humans, and appeared to have a very favorable safety profile

To investigate the involvement of the vB12 pathway in the metabolic phenotype, we treated Tbx1 +/ and Df1/ + mice postnatally with vB12 or PBS (vehicle) twice a week for 4 wk starting at 4 wk of age, after which the animals were euthanized and the brains collected