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It has been shown that inducing mitophagy in a way that is dependent on the small GTPases Rheb and NIX promotes mitochondrial OXPHOS, which in turn stimulates mitochondrial renewal, indicating that mitophagy is committed to the successful renewal of mitochondria [237]

Acknowledgements We would like to express our appreciation to the researchers who contributed to our review study

[DOI] [PubMed] [Google Scholar] 9.Grissom CB, Chagovetz AM, Wang Z

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