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Funding This work was supported by the Deutsche Forschungsgemeinschaft (DFG) SFB-TR 338 (LETSimmun)project number: 452881907, SFB 1526 (PANTAU), project number: 454193335

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We synthesized and cloned a library containing 164 sgRNAs, targeting the 44 TFs, and included 20 non-targeting control (NT) sgRNAs

doi: 10.3390/molecules201219800 101

In the central nervous system, niacin is known as a key mediator of neuronal development and survival ( Current evidence has shown that a deficit of mitochondrial energy metabolism is involved in the pathogenesis of migraine headaches ( Pantothenic acid Pantothenic acid is involved in the biosynthesis of coenzyme A, cholesterol, fatty acids, and acetylcholine ( Current evidence suggests that pantothenic acid deficiency causes neurological disturbances ( Pyridoxin Vitamin B6 consists of three main forms including pyridoxine, pyridoxamine, and pyridoxal