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48 LiK.JiangP.LiS.SunJ.QiC

Many of these effects are normalised by uncoupling of oxidative phosphorylation and by overexpression of MnSOD.20 ROS contribute also to the pathogenesis of neuropathy as clearly demonstrated by several experimental studies

After incubation for 12 h, a new peak at 3.26 ppm appeared corresponding to the -CH 2 protons of GSSG (Fig

Studies carried out with A

Intraneuronal aggregates of -syn that are intracellularly localized and bound to cellular membranes are capable of triggering ferroptosis through these aggregate-membrane interactions ( 3.2 Relationship between PD-related genes/proteins and ferroptosis PD pathophysiology is significantly influenced by genetic predisposition, with numerous gene loci linked to its development (133)
