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Neuroendocrine dysfunction in polycystic ovary syndrome
Increased stress susceptibility and impaired differentiation of astrocytes and neurons was found in co-cultures and in neural organoids generated from AxD patient-derived induced pluripotent stem cells with AxD-causing GFAP R239C mutation 334
it is called Collateral Sensitivity (CS) 14
doi: 10.1111/j.1365-2222.2007.02902.x
Dysregulation of the Wnt/-catenin pathway has been observed in vitiligo disease, which may explain the heightened vulnerability of vitiligo cells due to a decreased protective ability of this pathway (135)
