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This dual IDH1/IDH2 inhibitor demonstrated in the phase III INDIGO trial a median progression-free survival of 27.7 months compared to 11.1 months for the placebo, representing more than a two-fold improvement [26,27]

Spindle abnormalities were minimal at early time points but increased significantly by 24 hours in untreated oocytes

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The Basic Immunology of Asthma
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