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12 Another prospective cohort study of 36 patients with TBI and a minimally conscious state showed an improvement in arousal, aphasia, and cognitive function

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GH exerts autocrine/paracrine effects by binding to GHR in the same or a neighboring cell surface and initiating JAK2- and SRC-mediated signaling cascades, which decrease pro-apoptotic molecules (Bax and PPAR) and suppress caspase protein activation (Figure 4A)