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Description
Here we have identified that depletion of -ketoglutarate (KG) sensitizes HR-proficient cells to DNA-damaging agents by metabolic regulation of histone acetylation

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Screening the p53 status of human cell lines using a yeast functional assay
The patient do not suffer from any chronic diseases, also family history is not significant
Only a small amount of the rectal surface was visualized, and it was questionable whether there was any radiation proctitis
