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Description
Dissociated TXNIP combines with and activates the NLRP3 inflammasome to induce IL-1 expression in a NLRP3-ASC-caspase-1-dependent manner, thus causing inflammatory reactions

both agents were applied in Ca-free Ringers solution to isolate store-derived Ca signals

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Key hub genes, including SOD1, SOD2, and GPx family members, were downregulated, corresponding to decreased antioxidant enzyme activities in erythrocytes exposed to INH (36 mM)

PMID 15947186
