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Safe human dosing ranges for GA are between 0.015 and 0.229 mg/kg body weight per day ( It should be noted that different licorice preparations contain varying levels of GA and glycyrrhizin

Moreover, A peptide has been used in IN delivery studies aimed at reducing A fibrils and mitigating microglial and astrocytic activation, but the clinical trials were terminated due to cases of meningoencephalitis observed in some patients [111, 192]

Rzezniczak et al., 2011)

The olfactory region, in the upper nasal cavity, has a smaller mucosal area but is significant for IN drug delivery [57]

Using reaction time and co-contraction to differentiate acquired (secondary) from functional fixed dystonia