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10.1073/pnas.1215689109 27

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RH collected the data, performed the statistical analysis, and drafted the manuscript

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Given the high heterogeneity of ASD, treatment strategies should be tailored to the individual needs of each patient

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Alcohol-induced oxidative stress end-organ injury [2], [7], [10] is believed to be the results of mitochondrial damage [11], [12], [13], [14], [15] and decrease of ATP production [16]

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Cyclic vomiting syndrome (CVS) is a chronic disorder characterized by episodes of uncontrollable vomiting that are interspersed with asymptomatic or minimal symptom periods.1 CVS was described by Heberden in 1806 as a pediatric disease specified by recurrent vomiting and influenced by psychologic disorders.2 However, it is currently known that the syndrome can start in adulthood, with a similar clinical behavior in the two age groups.3 Vomiting episodes tend to be incapacitating, negatively impacting quality of life

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