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These include the induction of oxygen-consuming inflammation, that reduces the ability of the lungs to effect gas exchange, and anemia, vasoconstriction, and hemoglobin conversion that reduces the oxygen delivery capacity of the blood stream

Calcium leakage: They can interfere with calcium handling in muscles, leading to stiffness and cramping

CNS Drugs 35, 2137

It initiates rapid repair by enhancing keratinocyte and fibroblast migration, stimulating angiogenesis, and restoring tissue integrity

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