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Patients with pre-existing conditions including cardiovascular disease, liver disease, thyroid disorders, kidney disease, or gallbladder disease face particular uncertainty
Diabetologia 58 (4), 799808
Niacin can also have an antagonistic effect on gout medications: it elevates uric acid levels, which may counteract drugs like allopurinol or pegloticase that are meant to lower uric acid
J., Klein, S
Published human studies (Dhillo et al., JCEM, 2005) used IV bolus doses and observed rapid hormonal responses
