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Interestingly, in chronically insulin treated 3T3-L1 cells and fat explants from insulin resistant mice, only insulin-stimulated glucose uptake is decreased while insulin suppression of lipolysis is intact (121), effects which are explained by selective insulin resistance in adipocytes

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This case highlights the importance of timely treatment, such as administering vitamin B12, to avert possible neurological complications, underscoring the critical need for early diagnosis

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Hematologic and myeloproliferative disorders Several blood disorders drive B12 up by increasing the production of its carrier proteins
