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Metabolic diseases In addition to muscle and neurodegenerative conditions, alterations in NAD + levels and mitochondrial homeostasis are also observed in aging-associated metabolic diseases, particularly those conditions impacting highly mitochondrially-active tissues such as the kidney and liver 292294

Beyond alcohol and cocaine, the role of GlyT1 inhibition has been investigated in relation to nicotine-seeking behavior

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[DOI] [PubMed] [Google Scholar] 208.Briggs DT, Martin CB, Ingersoll SA, Barnum SR, Martin BK