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These findings suggest that NNMT may represent a promising therapeutic target for the development of RNAi drugs aimed at preventing or treating MetS (Van Haren et al., 2021

Long-Term Data: While short-to-medium term studies (up to several months) indicate safety, long-term safety data (over multiple years) in broad populations is still being gathered

Key finding: AOD 9604 (0.1-10 mcg/kg) promoted cartilage repair with 52% defect filling versus 8% in controls

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Because AOD9604 is studied in the context of selective fat metabolism modulation, adipocyte function regulation, and body composition effects, it is a subject in experiments related to metabolic health and weight regulationwithout implying outcomes outside of a research setting.