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Peroxynitrite affects the cumulus cell defense of metaphase II mouse oocytes leading to disruption of the spindle structure in vitro

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The precise regulation of redox balance is undoubtedly difficult, so the application of antioxidant therapy should be cautious before a systematic and comprehensive clinical evaluation, and the treatment plan should be adjusted based on followup examinations

Moore LE, et al

The GPx1 active site has the sequence LUG, where U is the catalytic selenocysteine
