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Description
Plant lignans and isoflavonoid phytoestrogens can decrease the conversion of androgens to estrone by inhibiting the cytochrome P450 enzyme aromatase, which can play a protective role in PCa
A number of intervention methods including surgical treatment, chemotherapy, radiotherapy, and targeted drug treatment have been tried, but their overall effect on managing cancers of digestive system is still unsatisfactory (Van Schaeybroeck et al., 2011
Angew Chem Int Ed 25:10581071 Sies H (1991) Oxidative stress: oxidants and antioxidants
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