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Description
After orally consuming Tramadol, it takes about an hour to show effect
BBB dysfunction may be specific to brain regions or to location along the arteriovenous axis
This creates effects that translate into antidepressant, anxiolytic, and neuroprotective actions in animal models

By repeating the above operations for three times, oxygen was removed
[ref] CYP2E1 and oxidative pathway: The liver breaks down most of the acetaminophen using sulfation and glucuronidation reactions, allowing for easy excretion
