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Side effects may include drowsiness, somnolence, lightheadedness, dry mouth, and a fast heart rate

Body cells and tissues are threatened continuously by damage caused by toxic free radicals and reactive oxygen species (e.g., peroxides), which are produced during normal oxygen metabolism, by other chemical reactions, and by toxic agents in the environment

doi: 10.3390/nu13061998

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187 The chemical reactivity of the epoxy-enone moiety is the basis for a postulated mechanistic link between the requirement for the 12( R )-LOX pathway of Cer-EOS metabolism and covalent binding of the ceramides (Scheme 82)