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Espinosa-Dez C, Miguel V, Vallejo S, Snchez FJ, Sandoval E, Blanco E, et al

Clinical studies have shown that the addition of thalidomide to the anti-TB treatment regimen resulted in substantial clinical and neuroradiological improvement, with a favorable safety profile and good tolerability in patients with tuberculous meningitis (TBM) [49]

For simplicity of presentation, the various mechanisms are discussed in the following order: Ia monosynaptic connection, Ia excitatory polysynaptic pathways, reciprocal Ia inhibition, group II pathways, decreased recurrent inhibition, alpha motoneuron hyperexcitability, gamma motoneuron hyperactivity, and group Ib inhibition

Although there is no corresponding research report at present, this method undoubtedly provides a new idea and strategy for the treatment of breast cancer

Bisulfite sequencing is still currently the gold standard method for detecting DNA methylation in patients with cancer [8]
