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Sepsis is a global health problem and, according to a previous study, in 2017, there were an estimated 48.9 million cases of sepsis worldwide, and nearly 11 million sepsis-related mortalities were reported, which accounted for 19.7% of the total global mortality (5)

Notably, there is a synergistic effect between smoking and occupational exposure to these carcinogens, further heightening the risk of bladder cancer (Zhang et al., 1994)

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Bleomycin in the setting of lung fibrosis induction: from biological mechanisms to counteractions