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Parkinson's disease: from pathogenesis to pharmacogenomics

The composition of these microbial communities varies across different body sites and is influenced by various factors including host genetics, age, sex, weight, diet, immune system, oxygen levels, pH, bile acids, gastrointestinal transit time, mucus production, disease states, medications, probiotics, certain surgeries like gastric bypass, and environmental factors (9-15)

Because CaSR maintains calcium homeostasis, its exaggerated response to calcium tells the body to excrete more calcium