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Nrf2/ARE-dependent genes code for several mediators of the antioxidant response, including glutathione S-transferases (GSTs), thioredoxin, NAD(P)H quinone oxidoreductase 1 (NQO-1), and heme oxygenase 1 (HO-1) (11)

De Miranda, B

These interactions ensure the correct positioning of the scissile peptide bond with respect to the catalytic zinc ion

Conversely, HFD-fed mice showed a marked reduction in GSH concentration without treatment, but coffee brew treatment in HFD-fed mice ameliorated GSH reduction (Fig

These findings indicate that the BIVID-MaP method can elucidate non-canonical RNA structural changes and their effects on the small-molecule binding that are undetectable by RNA secondary structure predictions