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[Google Scholar] 125.Vergalli J., Bodrenko I.V., Masi M., Moyni L., Acosta-Gutirrez S., Naismith J.H., Davin-Regli A., Ceccarelli M., van den Berg B., Winterhalter M., Pags J.-M

By applying the drug directly under the tongue (sublingual) or on the cheek (buccal), the medication undergoes a passive diffusion through the venous blood in the oral cavity, which bypasses the hepatic portal vein and flows into the superior vena cava

doi: 10.1016/j.tifs.2014.08.009 236

Increasing glutathione levels may help improve symptoms and reduce the incidence of bacterial infections [38, 39, 40]

Due to the stability problem a different method based on Tetramethyl (succinimido) uronium tetrafluoroborate can be also used