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The incubation with antioxidants abrogated the anti-proliferative response, suggesting that the oxidative stress induced by fumarate accumulation is responsible for the induction of senescence
In diabetic rat models with endotoxin-induced periodontitis, systemic administration of CMC 2.24 significantly inhibited alveolar bone loss while also attenuating both local and systemic inflammation
Mandecka A, Regulska-Ilow B
S2CID 20385802
