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Although NEM reacts with thiols by a very fast Michael addition reaction at neutral or slightly acidic pH, this reaction is reversible, and an excess of NEM should be used to avoid the possible migration of the maleimide group among different thiols 3

DOI: 10.1007/s12011-012-9397-6 91

Increased levels of 5-HT in peripheral blood could activate pancreatic -cells and increase their proliferation through the 5-HT3 receptor, leading to increased release of insulin and 5-HT by these cells [282]

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Epithalon (Epitalon) to tetrapeptyd o sekwencji Ala-Glu-Asp-Gly (alanina-kwas glutaminowy-kwas asparaginowy-glicyna