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Description
A Phase 2 Open-Label, Multicenter, Dose Optimization Clinical Study of the Safety, Tolerability, and Pharmacokinetic (PK) and Pharmacodynamic (PD) Profiles of Cfi-400945 As a Single Agent or in Combination with Azacitidine or Decitabine in Patients with Acute Myeloid Leukemia

doi: 10.1073/pnas.0906048106 [DOI] [PMC free article] [PubMed] [Google Scholar] 339
Future work to directly link the clock to regulation of GSH levels in the lens will be important in determining whether the clock can be used to help restore GSH levels in the lens

The bottle itself is brown

They also overproduce and secrete ECM components, leading to excessive ECM deposition in the myocardial interstitial and gradual replacement of myocardial tissue with fibrosis (249)
