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That said, HRT is not balancing hormones, it can more accurately be described as hormone supplementation

doi: 10.1016/j.gene.2013.08.077

B12, a vitamin crucial for energy metabolism, may boost energy levels, potentially increasing motivation for exercise a key component of sustainable weight loss

Notably, the body stores some vitamin B12 in the liver, which can last for years

In addition, it is possible that in spared brain regions, the aggregation process is assisted and controlled by cellular-specific quality control mechanisms in such a way that toxicity is maintained subthreshold, avoiding cell dysfunction and death
