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Description
Plantar injection of IGF-1 increased the expression of G-protein-coupled receptor kinase 2 (GRK2) in ipsilateral DRG, which can relive the mechanical hyperalgesia
Peptide signaling is generally more direct than hormone cascades

In conclusion, the selection of an appropriate analytical method is crucial and depends on the specific requirements of the analysis

10.4049/jimmunol.166.2.1206 52 DangP

We detected higher oxidized states of Cys 170 of phosphofructokinase (PFK), Cys 247 of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Cys 379/80 of phosphoglycerate kinase (PGK) and Cys 49 and Cys 326 of pyruvate kinase M (PKM), which were all reported to interfere with either the primary or secondary function of these enzymes 32,33,34,35
