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[37] [61] The concentrations of the main neurotransmitters involved in reward circuitry and executive functioning, dopamine and norepinephrine, increase dramatically in a dose-dependent manner by amphetamine because of its effects on monoamine transporters

doi: 10.1177/1933719115592713 [DOI] [PubMed] [Google Scholar] 157

Piperine works by inhibiting metabolic enzymes ( glucuronidation pathways) in the liver and intestinal wall, substantially increasing absorption of co-administered compounds

Cancer Res

Compared to an isocaloric control diet, the high carbohydrate-high calorie diet was safe, tolerable and effective in delaying weight loss and prolonging survival in the patients (Wills et al., 2014)