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Importantly, c-MET has also been associated with chemoresistance by bypassing traditionally clinically inhibited signals such as EGF

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One advantage of using CDs for imaging cancer cells is their ability to emit light in the near-infrared region, which can penetrate deeper into tissues than visible light

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Additionally, disruptions in the blood-brain barrier in those with neurocognitive symptoms have been observed, as well as hypoperfusion in various organs, contributing to end-organ dysfunction [364, 365]