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Three main pathways are thought to be involved in the interactions between the gut microbiota and the brain: 1) direct and indirect signaling through chemical transmitters, such as hormones, neurotransmitters, or microbial metabolites (e.g., short-chain fatty acids, or SCFAs), that can be directly synthesized by the gut microbiota or have their levels modulated by gut microbiota
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Consequently, BACH1 stabilization leads to the upregulation of key growth factors and their receptors, driving vascular endothelial cell proliferation and tube formation to promote angiogenic repair
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