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321 In a hepatocellular tumorigenic model, GPX4 deletion-induced ferroptosis results in the release of high levels of HMGB1, thereby promoting the recruitment of immunosuppressive MDSCs

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10.1093/ageing/afab044 Age Ageing 142 LinszenM

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in this situation, NAC reduces the risk of hepatotoxicity to 100 mg/L, the presence of renal failure or ARDS, or progression of the toxidrome despite alkalinization therapy (39)