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Same could be said for diet and the vilification of fat and cholesterol

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4.2 Combined strategies of immune, antivascular, and radiotherapy based on metabolic pathways Metabolic remodeling, vascular normalization, and T-cell infiltration can form a synergistic cascade: inhibiting HIFVEGF signaling and dysregulated lipid metabolism may reduce myeloid-mediated immunosuppression, improve perfusion and oxygenation, and enhance CD8+ T-cell effector function, thereby providing a metabolic rationale for synergy between TKIs/VEGF inhibitors and ICIs

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[DOI] [PMC free article] [PubMed] [Google Scholar] [176].Zaitsev AV, Smolensky IV, Jorratt P, Ovsepian SV, Neurobiology, Functions, and Relevance of Excitatory Amino Acid Transporters (EAATs) to Treatment of Refractory Epilepsy, CNS Drugs 34(11) (2020) 10891103

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