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The clinical anatomy of the inferior vena cava: A review of common congenital anomalies and considerations for clinicians

In human, TMAO is mainly derived from gut, where the gut microbiota converts dietary nutrients into TMA, which is absorbed into the bloodstream through the intestinal mucosa, and then transformed into TMAO by hepatic flavin monooxygenases (FMOs) in the liver (Zeisel and Warrier, 2017

As an alternative drug delivery route, topical medications have not shown promising results and need further evaluation in future trials

Dietary precursors of trimethylamine in man: a pilot study

doi: 10.3390/cells10030660 119 AdhikariUKKhanRMikhaelMBalezRDavidMAMahnsDet al