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doi:10.1007/s00280-021-04361-8 Schaff LR, Lobbous M, Carlow D, et al
10.1007/s00401-022-02498-1 Acta Neuropathol
is that they have evolved as a result of a need for a higher regulatory input in Wnt signaling in the adult tissue stem cells frequently seen in long-lived vertebrates (Clevers et al., Lgr5 especially, has garnered much attention the last few years as a high fidelity marker of stem cells in several regenerating tissues (Schuijers and Clevers, 2012)
doi: 10.1016/S0140-6736(19)31138-9
TomaszewskaERudykHSwietlickaIHulas-StasiakMDonaldsonJArczewskaMet al
