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Furthermore, acyl-carnitines have important roles in the regulation of cellular energetics and mitochondrial functioning, including roles in the central nervous system (CNS) 41,42

These include itsactions on acetylcholine synthesis, membrane stability, nerve growth factor production, and cerebral blood flow

Research in pigs, however, has demonstrated that the bioavailability of the minerals in chelated forms is not always greater and is sometimes lower than the bioavailability of elements in inorganic salts

Consequently, reducing circulating TMAO has emerged as a potential therapeutic approach for heart failure [56]