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Instead, peptides will find niche applications by targeting intracellular pathways inaccessible to antibodies, offering a complementary rather than competitive therapeutic approach

At the molecular level, reduced NNMT activity shifts cellular methylation patterns, potentially altering epigenetic modifications via changes in SAM/S-adenosylhomocysteine (SAH) ratios

Caers J, Duray E, Vrancken L, Marcion G, Bocuzzi V, De Veirman K, et al

5c and Supplementary Figs

Higher plant APR are homodimers with each monomer formed by an N-terminal domain binding a [4Fe-4S] cluster and bearing the APR activity and a C-terminal GRX-related domain (Figure 2 and Supplementary Table 2)