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Most participants reported consuming the full dose, but 36% consumed a lower dose, due to adverse effects at higher dosages (15%) or other non-AE reasons (21%)

For example, (1) critical studies in laboratory animals were conducted only recently

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Gene knockdown by RNA silencing siRNAs were transfected into THP-1 macrophages with LipoRNAi MAX transfection reagent (Invitrogen, #13778100)