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Ninomiya JK, LItalien G, Criqui MH, Whyte JL, Gamst A, Chen RS

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It is noteworthy that the disulfide linkage between homocysteine and the cysteine-rich domain of annexin II is responsible for the homocysteine-specific inhibition of t-PA binding to annexin at the cell surface (Hajjar et al, 1998)

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Avoid repeated freeze-thaw cycles and handle under aseptic conditions to preserve stability
