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While an updated meta-analysis of 32 randomized trials including 24,389 patients showed SDD was associated with lower mortality, it should be noted that the vast majority of positive trials were published well over a decade ago and are in settings with low antimicrobial resistance [327]

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As the bodys main intracellular thiol antioxidant , glutathione neutralizes reactive oxygen species and participates in cellular detoxification pathways (for example as a cofactor for glutathione peroxidase and in conjugation reactions) [5] [6]

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