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Kanakkanthara A, Kurmi K, Ekstrom TL, Hou X, Purfeerst ER, Heinzen EP, Correia C, Huntoon CJ, OBrien D, Wahner AE, Hendrickson SC, Li DH, Oberg AL, Hitosugi T, Kaufmann SH, John Weroha S, Karnitz LM (2019) BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents

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On day 0, blood samples were collected via anesthesia-induced cardiac puncture and stored for plasma glycerol analysis

In clinical deficiency states, mostly as a result of insufficient resorption of vitamin B12, such as after extensive resection of the small intestine and irritation of the small intestine (dysbiosis of the intestine), the resorption area in the intestine is reduced or blocked

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