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Indeed, CEBPB and EP300 , along with genes related to the Mitogen-Activated Protein Kinase (MAPK) signaling cascade such as MAP3K1 , MAP2K2 , and MAP3K11 were significantly upregulated in RMC tumor cells following treatment with nivolumab plus ipilimumab, (Fig

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Note: The review article states much LOWER quantities may be biologically active
